2023-2024 / BIOC0232-1

Macromolecular biochemistry

Duration

25h Th

Number of credits

 Master in chemistry (120 ECTS)3 crédits 

Lecturer

Moreno Galleni

Language(s) of instruction

English language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Editer

1) Chemical properties of amino acids and of the polypeptide chain
1.1 Nature of the polypeptide chain
1.2 Amino acids
1.3 Detection of aminoacids, peptides and proteins
1.4 Determination of the protein size
1.5 Determination of the aminoacid sequence
1.6 Chemical synthesis of peptides
1.7 Non ribosomal synthesis of peptides
1.8 Post transcription modification of the polypeptide chain
2) Mechanism of protein localization in prokaryotes and eukaryotes
3) Interactions affecting the properties of proteins
3.1 Nature of non covalent interactions
3.2 Intramolecular interactions
4) Conformational properties of proteins
4.1 Secondary and ternary structures of proteins
4.2 Spectroscopic properties od proteins in solution
5) Biophysical properties of soluble and membranar properties

Learning outcomes of the learning unit

The course will be devoted to the structural and chemical properties of proteins.

Prerequisite knowledge and skills

Lectures in general biochemistry
Thermodynamic and classical physic
Organic chemistry

Planned learning activities and teaching methods

30 h of practical course, dedicated to protein purification and enzyme catalysis

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course

Recommended or required readings

Syllabus + power point presentation

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire, open-ended questions )


Additional information:

Written exam with a MCQ (20 questions) ans two open questions
 

Work placement(s)

Organisational remarks and main changes to the course

Contacts

Galleni Moreno, room 2/10, Institut de Chimie , B6a. Sart Tilman
Tel:04/3663549 - Fax:04/3663364 - Email:mgalleni@ulg.ac.be

Association of one or more MOOCs