2023-2024 / BIOC0340-1

Clinical Chemistry (Part I)

Duration

22h Th, 12h SEM

Number of credits

 Master in pharmacy (120 ECTS)4 crédits 

Lecturer

Etienne Cavalier

Language(s) of instruction

French language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

The course is given in two parts. Part I consists of 2 modules.

The 1st module corresponds to the analytical part of the Clinical Chemistry discipline. We will see the various techniques used in the laboratory, their limits, how to validate the methods, how to establish reference values, how to interpret an internal control and an external control. Biological variability and its applications will also be discussed, as well as sensitivity, specificity, and positive and negative predictive values.

The lectures in this module will be delivered face-to-face. There will be a practical exercise session. Students will be provided with powerpoints, video clips and will be able to practice answering questions on the course to ensure their understanding through online exercises via Socrative and e-Campus.

The second module will be devoted to the exploration of different pathologies in the field of haematology. We will see the exploration of the different types of anaemia, the exploration of the different types of leukaemia and myeloma and the exploration of the blood coagulation pathologies. Video clips and powerpoints will be available to students, as well as online self-assessment questionnaires (Socrative/e-Campus).

A face-to-face session will be organised, consisting of work in small groups (role-playing) where students (playing the role of the pharmacist) will be confronted with a patient (played by a supervisor from the Clinical Chemistry Department). The latter will arrive with a lab tests results representing one of the cases presented during the courses. The student pharmacists will be challenged by the patient mentor.

The examination will cover both theoretical knowledge via a T/F MCQ questionnaire and exercises (for module I) and clinical cases.

 



 

Learning outcomes of the learning unit

The objective of the course is the knowledge of the biochemical lesions which cause diseases, that the abnormality comes from an error of biosynthesis due to gene mutation, or that it results from an acquired disturbance of metabolic regulation. The course must thus lead the student to include/understand the biochemical mechanisms which underlie normal and pathological phenomena . The course will find its prolongation in the practical applications of biochemical diagnosis in the clinical laboratory.

Prerequisite knowledge and skills

Human biochemistry, Elements of general pathology.

Planned learning activities and teaching methods

Traditional pedagogy,  role-playing. Self-evaluation questionnaire.

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course

Recommended or required readings

Power-point of the lectures

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire, open-ended questions )


Additional information:

Written 

The examination consists of a V/F part and a part with open questions (exercises, clinical cases).

Each part is worth 50% of the final mark. A mark of at least 8/20 in each of the 2 parts is required to pass the examination.

If a mark of less than 8/20 is obtained in either part, this will be taken as the final mark for the examination.

Work placement(s)

Organisational remarks and main changes to the course

Contacts

Prof E. Cavalier
Dpt of Clinical Chemistry, Route 52, Porte 53

CHU de Liège
Sart Tilman, 4000 Liege
Secretariat: 04/3238822

E-mail : etienne.cavalier@chuliege.be

Association of one or more MOOCs