2023-2024 / BIOC9239-1

Structural bioinformatics

Duration

25h Th, 25h Pr

Number of credits

 Master in bio-informatics and modelling (120 ECTS)3 crédits 

Lecturer

Frédéric Kerff

Coordinator

Frédéric Kerff

Language(s) of instruction

English language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Objectives and program: 1) the tools needed for visualization and analysis of biological macromolecules,
2) an overview of protein modeling methods: homology modeling, ab initio modeling, proteins and ligands, docking methods, etc ...
The course will cover
- a reminder of the protein structure (if necessary ...),
- an introduction to the Protein Data Bank and description of a PDB file,
- an introduction to the Pymol visualization program and TPs on its use,
- the use of 3D structural analysis software (deepview software, PDBePISA)
- modeling by homology - Introduction to the Yasara and TP program on its use
- Protein-Ligand interactions - Introduction to AUTODOCK software

Learning outcomes of the learning unit

Prerequisite knowledge and skills

Planned learning activities and teaching methods

The use of the different software discussed requires the use of a laptop.

Mode of delivery (face to face, distance learning, hybrid learning)

Face to face

Recommended or required readings

Power points Softwares access

The examination will consist in the realization of a work and report based on the study of a practical case whose title will be given beforehand.

Work placement(s)

Organisational remarks and main changes to the course

25 lessons of 2 hours.
   

Contacts

Dr Frédéric Kerff- Tél. 04/366.36.20 - E-mail : fkerff@uliege.be
   

Association of one or more MOOCs