Organic chemistry

Duration

50h Th

Number of credits

Lecturer

Thibault Gendron, Jean-Christophe Monbaliu

Coordinator

Jean-Christophe Monbaliu

Language(s) of instruction

English language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Organic Chemistry consists in a series of lectures building upon the fundamentals of organic chemistry taught in Organic Chemistry I, II and II (Bachelor). The course starts with a thorough introduction on the concepts of retrosynthetic analysis and the principles of total synthesis. The student is next confronted to a selection of classical total syntheses for the preparation of complex bioactive organic molecules. In addition to total synthesis, this series of lectures also proposes introductory concepts of Green Chemistry and the main challenges for Organic Chemistry in the 21st century. Some additional concepts related to reactivity and selectivity are also presented for the optimization of chemical syntheses and the reduction of their environmental impact. A large diversity of examples and exercises are used to illustrate the theoretical concepts.

Learning outcomes of the learning unit

• Get a retrosynthetic-oriented approach for the synthesis of complex organic molecules and practice conceptual total synthesis
• Get familiar with the environmental impact of Organic Chemistry and the principles of Green Chemistry
• Rationnalize reactivity and selectivity

Prerequisite knowledge and skills

Fundamental concepts of organic chemistry (bachelor degree)

Planned learning activities and teaching methods

Exercises
A large diversity of examples and exercises are used to illustrate the theoretical concepts.
 
Lab practice
Nihil
 
Homework assingments will reinforce and extend the concepts (25% of the final evaluation)

Mode of delivery (face to face, distance learning, hybrid learning)

 
Delivery of material in a lecture format, face-to-face. Possibility of e-learning (online additional references and resources);
 

Recommended or required readings

Slides and additional resources will be made available to the students (myuliège). A large diversity of examples and exercises are used to illustrate the theoretical concepts.
 

• Organic Chemistry, J. Clayden, N. Greeves, S. Warren and P. Wothers, Oxford University Press, 2012, ISBN 9780199270293
• Classics in Total Synthesis 1-3, K.C. Nicolaou, Wiley VCH.
• Modern Physical Organic Chemistry, E. V. Anslyn, D. A. Dougherty, University Science Books, 2006 (ISBN 978-1-891389-31-3)

The overall theoretical and practical competences will be assessed during a written exam (4 h, January examination session, 75% of the evaluation). The exam consists mostly in solving concrete syntheses and applying the various theoretical concepts. A second examination session will be rescheduled for grades below 10/20 with similar criteria as for the first examination session.

Work placement(s)

Organisational remarks and main changes to the course

Contacts

Jean-Christophe M. Monbaliu
tel 04 366 35 10 ; email jc.monbaliu@uliege.be  

Association of one or more MOOCs

Items online