Duration
25h Th
Number of credits
| Master in chemistry (120 ECTS) | 3 crédits |
Lecturer
Language(s) of instruction
French language
Organisation and examination
Teaching in the first semester, review in January
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
The course is a practical application of NMR techniques studied in the course on Biological chemistry (CHIM0729)
After a lesson summarizing the theoretical principles and practicalities of different NMR experiments, students will be asked to record themselves their own experiences protein in solution interacting with ligands.
The proposed experiments are the following 1D 1H with water suppression, 2D HSQC (HN).
Learning outcomes of the learning unit
Objective 1: Acquiring the ability to record adequately all NMR experiments required for the analysis of biological macromolecule in water Objective 2: To understand the spectral information obtained by applying a sequence of pulses. Objective 3: to choose experiences tailored to their research.
Prerequisite knowledge and skills
Course on structural analysis: CHIM-9291 Course on biological Chemistry CHIM-0729
Planned learning activities and teaching methods
Practical work on the NMR spectrometer. Preparation of the biological samples. Analysis of the spectra with appropriate computer programs : TOPSPIN
Mode of delivery (face to face, distance learning, hybrid learning)
The course schedule will be determined with the students according to the availabilities of each and the availability of the spectrometer.
Recommended or required readings
course CHIM-9291 (structural analysis) cours CHIM-0729 (biological chemistry )
Written report on the analysis performed by the students.
Work placement(s)
Organisational remarks and main changes to the course
Contacts
C. Damblon (C.Damblon@ulg.ac.be)