2023-2024 / CHIM9245-1

Advanced chromatographic techniques

Duration

15h Th, 3h Pr

Number of credits

 Master in bioengineering : chemistry and bio-industries (120 ECTS)2 crédits 

Lecturer

Giorgia Purcaro

Language(s) of instruction

English language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Lectures given in English
- Practical aspects of chromatography (Gas liquid chromatography and high performance liquid chromatography). - Multidimensionnal and hyphenated separations techniques (GCxGC, LC-GC and LCxLC) - Deeper understanding of the use of Mass Spectrometry in chromatography
- Exercises : Case studies.
- Seminars

Learning outcomes of the learning unit

The course focuses on modern and advanced chromatographic techniques for the analysis of molecules from complex biological systems
After completing the course the student is expected to - understand the different techniques (chemical analysis, derivatization, chromatography,...) for the characterization of the analytes as well as the use of state-of-art chromatographic methods;
- describe and discuss about the different potentialities and applicability of the advanced chromatographic techniques
- be able to discuss case studies including the theoretical aspects of the course.

Prerequisite knowledge and skills

--CHIM9246-A Analytical chemistry: instrumental techniques
-- CHIM9242-4 - Fundamentals of quantitative analytical chemistry
-- CHIM9238-3 - Analytical Chemistry
-- CHIM9255-3 - Organic Chemistry
-- BIOL2017-5 - Biological Chemistry
-- BIOL2019-1 - Theoretical and physical chemistry applied to structural analysis of biomolecules

Planned learning activities and teaching methods

Face-to-face
It is mandatory to attend all the seminars

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course


Additional information:

Lectures : 15h
Seminars : 3h

Recommended or required readings

Course notes
Hyphenations of Capillary Chromatography with Mass Spectrometry, Luigi Mondello and Peter Q. Tranchida (Eds), Elsevier
Comprehensive Sampling and Sample Preparation, Elsevier, Academic Press, 2012. ISBN: 978-0-12-381374-9
Handbook of Advanced Chromatography/ Mass Spectrometry Techniques, Eds William Craig Byrdwell and Michal Hol¿apek, Elsevier, Academic Press and AOCS Press. eBook ISBN: 9780128117330; Paperback ISBN: 9780128117323
Gross JH. Mass spectrometry. 3rd ed. Switzerland: Structure. Springer; 2017.

Exam(s) in session

Any session

- In-person

oral exam

Continuous assessment


Additional information:

Oral examination in English (hybrid class) (100%)

Work placement(s)

Organisational remarks and main changes to the course

Contacts

Giorgia Purcaro (Professor ) +32 81/62.22.20 gpurcaro@uliege.be

Association of one or more MOOCs