University of Liege | Version française
Academic year 2014-2015Value date : 1/10/2014
Version 2013-2014
SBIM0462-1  Pharmacology and addiction clinic

Duration :  10h Th
Number of credits :  
Master in Biomedicine, Research Focus, 2nd year2
Lecturer :  Emmanuel Pinto
Language(s) of instruction :  
French language
Course contents :  
The main purpose of this course is to provide students with the molecular mechanisms shared by the addictive disorders (neuro-anatomy of the reward circuits of the brain, molecular, genomic and structural adaptation linked to addiction).
We also review the main addictive substances on a pharmacological, epidemiolocal, clinical and theapeutic point of view. Alcohol dependance is more precisely studied under its genetic, clinical and therapeutic specificities.
Learning outcomes of the course :  
The objective is to give the student a general overview of the common neurobiological mechanisms shared by the main addictions. Key-informations about the main addictive substances is a secondary objective of this course.
Prerequisites and co-requisites/ Recommended optional programme components :  
Planned learning activities and teaching methods :  
Ex cathedra courses with Powerpoint support.Key articles provided
Mode of delivery (face-to-face ; distance-learning) :  
Face-to-face
Recommended or required readings :  
Powerpoint presentationKey-articles :
  • Bowirrat, A., & Oscar-Berman, M. (2005). Relationship between dopaminergic neurotransmission, alcoholism, and Reward Deficiency syndrome. Am J Med Genet B Neuropsychiatr Genet(1), 29-37.
  • De Witte, P., Pinto, E., Ansseau, M., & Verbanck, P. (2003). Alcohol and withdrawal : from animal research to clinical issues. Neurosci Biobehav R(27 ), 189-197.
  • Koob, G. F., & Le Moal, M. (1997). Drug Abuse: Hedonic Homeostatic Dysregulation. Science, 278(5335), 52-58.
  • Young, R. M., Lawford, B. R., Nutting, A., & Noble, E. P. (2004). Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene. Addictive Behaviors, 29(7), 1275-1294.
Assessment methods and criteria :  
Multiple choices questionnaire
Work placement(s) :  
Organizational remarks :  
Contacts :  
epinto@ulg.ac.be



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