2023-2024 / BIOL2029-1

Introduction to clinical biology

Duration

20h Th

Number of credits

Lecturer

Etienne Cavalier, Corinne Charlier, André Gothot, Marie-Pierre Hayette

Coordinator

N...

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Clinical biology includes 4 different disciplines, the introduction will be done by 4 professors:

Clinical Microbiology (Marie-Pierre Hayette)

- Description of the different tasks - missions of a clinical microbiology laboratory and the organizational mode.
- The best strategies to use appropriately the laboratory and the limited available ressources.
- The mostly used analytical methods are shortly described, including the quality assurance background.
- The worldwide problem of the increased of emerging multi-resistances to antimicrobial agents among bacteria and the major role of the laboratory for their detection.
- Towards tomorow microbiology and automation
- Management of biosecurity regarding handling of pathogenic microorganims.

Clinical chemistry (Etienne Cavalier)

- Description of the different methods used in the laboratory

- Elements of interpretation of clinical chemistry results

Hematology (André Gothot)

During this part, the main cytology and coagulation analyses are reviewed.

Clinical toxicology (Corinne Charlier)

In the course, the main tasks of the Toxicology department are presented and the main reasons to ask for a therapeutic monitoring are described and explained. Different areas of activity of a university toxicology department are illustrated. 

Learning outcomes of the learning unit

Clinical Microbiology (MP Hayette)
At the end of this course, students will be:

  • able to describe the different tasks - missions of a clinical microbiology laboratory and the organizational mode.
  • able to give clear and structured information towards the rational choice of analytical efforts within a cost-effective background for health policy.
  • able to understand and to explain the main used analytical methods within a quality assurance background.
  • aware of the increased of emerging multi-resistances to antimicrobial agents hapenning among bacteria and of the major role of the laboratory for their detection.
  • able to provide a short overview of the expected evolution in microbiology and automation
  • aware of the biosecurity needs and how to manage handling of pathogenic microorganims.
    Clinical chemistry (Etienne Cavalier)
  • At the end of this course, students will be able to understand how the differents methods work in clinical chemistry laboratory. They will be able to interpret
    Hematology (André Gothot)
At the end of this course, students will be able to understand:
  • the principles of cytology and coagulation tests
  • their interpretation in different clinical contexts
  • the methodology used to set up a validation report
    Clinical toxicology (Corinne Charlier)
Student needs to understand the reasons why bioavailabilty of therapeutuc drugs can vary from each other but also from time to time for a same person. 
He will be able to understand the main role of therapeutic monitoring. 

Prerequisite knowledge and skills

Prerequisite or corequisite units are presented within each program
Cours de Bac 3 microbiologie clinique, le laboratoire de microbiologie clinique (MP Hayette)

Planned learning activities and teaching methods

Lectures and discussion or visioconferences or podcasts

Mode of delivery (face to face, distance learning, hybrid learning)

Blended learning


Additional information:

Clinical microbiology:
Face to face or visioconferences or podcasts Slide sets of all lectures are available online on the university website through "myULg".
Clinical toxicology:

Face to face or visioconferences or podcasts
Diaporama available on the university website. 
 
Clinical chemistry:

Face to face or visioconferences or podcasts
Power-point available on the university website.
 
Hematology:

Face to face or online lessons on Lifesize. The recorded lessons are available as posdcasts afterwards.   

Recommended or required readings

Clinical microbiology:

Required to prepare exams: Slide sets of all lectures available online on the university website through "myULg".

A non exhaustive list of text-books can also be useful but they are not compulsory.









  • Bactériologie médicale - Techniques usuelles
    2ème édition
    François DENIS, Marie-Cécile Ploy, Christian Martin, Edouard Bingen, Roland QUENTIN
    Editeur: Elsevier Masson. 11/2011
    ISBN: 9782294096686
  • Numerous references are available for reading /downloading on the website of the American Society for Microbiology (ASM):

    http://clinmicro.asm.org/index.php/bench-work-resources

Clinical toxicology:
Many reference books
For example : TOXICOLOGIE CLINIQUE Chantal Bismuth et al, Médeine Sciences, Flammarion
 

Clinical chemistry:



  • Biologie médicale - Marqueurs actuels et perspectives.G. Durand & JL Beaudoux


 

Hematology:

Dacie and Lewis, Practical Haematology, Churchill Livingstone.

  

Exam(s) in session

Any session

- In-person

oral exam

Written work / report


Additional information:

Students will be required to complete a written assignment in the form of an analysis of an article or a report on a clinical biology topic. The work will be supervised by one of the four course teachers.

The written work will be a maximum of 5 pages, 11 gauge, 1.5 line spacing (excluding cover page and bibliography). The student will present his/her work orally in 10 minutes (10 slides).

Work placement(s)

  • 4-6 months internship opportunity during last year of master (final thesis)
  • Other lab internship opportunities

Organisational remarks and main changes to the course

Contacts

Clinical microbiology department
University Hospital of Liège, B-23 Sart Tilman,
4000 LIEGE   Belgium

Secretary
PFor any contact or appointment request, please address your demand to the secretary Mrs MC Lhôte

Phone: 00.32.4.366.24.39

Telecopy: 00.32.4.366.24.40

email: micromed@uliege.be, stephanie.wauquier@chuliege.be

 

Professor
Prof. MP Hayette, mphayette@uliege.be

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Clinical toxicology department
University Hospital of Liège, B-23 Sart Tilman,
4000 LIEGE   Belgium

Secretary

003243237683


Professor

Prof. Corinne Charlier, c.charlier@chuliege.be

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Clinical chemistry department
University Hospital of Liège, B-23 Sart Tilman,
4000 LIEGE   Belgium

Secretary
  D. Jeanne (delphine.jeanne@chuliege.be): 04/3668822

Professor

Prof. Etienne Cavalier

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Biological haematology department
University Hospital of Liège, B-35 Sart Tilman,
4000 LIEGE   Belgium

Secretary
Mrs Cécile Henet, hematobio@uliege.be, 04/366 75 36

Professor
Prof. André Gothot, agothot@uliege.be

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Association of one or more MOOCs

Items online

Introduction à la biologie clinique, partim Toxicologie (Podcast 3)
Clinical and Forensic Toxicology