2023-2024 / SANT4031-1

Specific clinical domain

Clinical examination - general semiology

Diagnostic measurements - supplementary investigations

Special Pharmacology

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Biochemistry and normal and pathological human physiology, Digestive system

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Biochemistry and normal and pathological human physiology, Cardiovascular system

Biochemistry and normal and pathological human physiology, Respiratory system

Biochimie et physiologie humaines normales et pathologiques, Système nerveux

Duration

Clinical examination - general semiology : 4h Th, 6h Pr.
Diagnostic measurements - supplementary investigations : 5h Th
Special Pharmacology : 20h Th
Biochemistry and normal and pathological human physiology, Endocrine system and metabolism : 15h Th
Biochemistry and normal and pathological human physiology, Digestive system : 15h Th
Biochemistry and normal and pathological human physiology, Nephro-urinary system : 10h Th
Biochemistry and normal and pathological human physiology, Cardiovascular system : 10h Th
Biochemistry and normal and pathological human physiology, Respiratory system : 10h Th
Biochimie et physiologie humaines normales et pathologiques, Système nerveux : 5h Th

Number of credits

 Master in nursing sciences10 crédits 

Lecturer

Clinical examination - general semiology : Bernard Lambermont
Diagnostic measurements - supplementary investigations : Edmond Brasseur
Special Pharmacology : Vincent Seutin
Biochemistry and normal and pathological human physiology, Endocrine system and metabolism : Philippe Kolh
Biochemistry and normal and pathological human physiology, Digestive system : Didier Cataldo
Biochemistry and normal and pathological human physiology, Nephro-urinary system : Didier Cataldo
Biochemistry and normal and pathological human physiology, Cardiovascular system : Philippe Kolh
Biochemistry and normal and pathological human physiology, Respiratory system : Didier Cataldo
Biochimie et physiologie humaines normales et pathologiques, Système nerveux : Pierre Maquet

Substitute(s)

Biochimie et physiologie humaines normales et pathologiques, Système nerveux : Gaëtan Garraux

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Clinical examination - general semiology

Ce cours a pour mission d'enseigner les bases de la sémiologie médicale aux infirmières de master en soins infirmiers.

 

Diagnostic measurements - supplementary investigations

It is an introduction to the concepts of prescriptions of complementary examinations for chronic pathologies, familiarization with radiological vocabulary and clinical biology. The main indications and contraindications will also be discussed.

Special Pharmacology

see in french

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

The course deals with normal and pathological human biochemistry and physiology, partim endocrine system and metabolism. In particular, it encompasses the following chapters:
1. Introduction
2. Mechanisms of action of hormones
3. The hormones of energy metabolism      
Energy metabolism      
Insulin and diabetes      
Glucagon      
Adrenaline      
Glucocorticoids      
Thyroid hormones
4. Gastrointestinal hormones
5. Water, electrolytes and mineral elements
6. Growth
7. Reproduction
Chapters VIII (cytokines) and IX (mediators) are removed from this year's materia

Biochemistry and normal and pathological human physiology, Digestive system

The course aims at allowing students to be able to understand human biochemistry and physiology

The different systems will be part of the course:

I. Cardio-vascular system. 

1. Elements of cardio-vascular physiology
2. Cardiac pump
3. Vascular System
4. Cardio-vascular homeostasis : cardiac output and arterial pressure
5. Principles of cardio-vascular physiopathology
6. Arterial hypertension
7. Coronary insufficiency
8. Cardiac failure


II. Respiratory system

1. Introduction to respiratory system 

2. Ventilation

3. Diffusion 

4. Circulation

5. Blood gazes

6. Control of pH

7. Gaz exchanges

8. Respiratory mechanics

9. Control of ventilation

10. Unusual conditions (altitude...). 


III. Digestive system 

1. Introduction

2. Regulation processes

3. Energy and metabolism

4. Regulation of intakes

5. Mouth

6. Oesophagus

7. Stomach

8. Hormons of digestive tract

9. Pancreas

10. Intestine absorption 

11. Liver 

12. Colon 

 
IV. Nephro-urinary system 

1. Introduction

2. Glomerular filtration

3. Tubular function

4. Water and ions regulation

5. Kidney pathophysiology 

6. Urinary tract


V. Endocrine system and metabolism

 

The course concerns human biochemistry and physiology, partim endocrine system and metabolism. In particular, it encompasses the following chapters:

1. Introduction

2. Mechanisms of action of hormones

3. The hormones of the energetic metabolism

   Energetic metabolism

   Insulin and diabetes

   Glucagon

   Epinephrine

   Glucocorticoids

   Thyroid hormones

4. Gastro-intestinal hormones

5. Water, electrolytes, and mineral elements

6. Growth

7. Reproduction

8. Cytokines

9. Mediators

 
VI Nervous system

Système sensoriels somatiques : somesthésie, vision, audition, gustation, olfaction

Système moteur somatique : unité motrice, contrôle segmentaire des unités motrices, contrôle supra-segmentaire, apprentissage

Cognition, émotion, comportement

Eveil et conscience

Homéostasie

Biochemistry and normal and pathological human physiology, Nephro-urinary system

The course aims at allowing students to be able to understand human biochemistry and physiology

Nephro-urinary system 

1. Introduction

2. Glomerular filtration

3. Tubular function

4. Water and ions regulation

5. Kidney pathophysiology 

6. Urinary tract

Biochemistry and normal and pathological human physiology, Cardiovascular system

The subject of this module relates to  Normal and Pathological Human Biochemistry and Physiology, partim cardiovascular system, broken down in the following chapters:  
The heart pump (Chapters I to V):  
- Functional architecture (Chapter I)      
   - Heart chambers      
    - Valvular apparatus  
- The automaticity of the pump (Chapter II)
    - The action potential  
    - Neuro-vegetative modulation
- The cardiac cycle (Chapter III)
   - The driving unit
   - The pressure-volume loop  
- Ventricular performance (Chapter IV)
   - The concept of preload
   - The concept of afterload
   - The concept of contractility  
- Myocardial energetics (Chapter V)
The vascular system (Chapter VI):  
- The laws of blood flow (Chapter VI)
   - Bernoulli's law
   - Darcy's law
   - Hagen-Poiseuille's law
- Functional architecture (Chapter VI)
   - Vascular resistance
   - Arterial elasticity  
- The blood pressure wave (Chapter VI)  
- Vasomotricity (Chapter VI)    
   - Mechanical self-regulation
   - Metabolic self-regulation
   - The endothelial function  
Cardiovascular control (Chapter VII)
- The relationships of cardiac output
- Control of blood pressure
   - The barosensitive reflex
   - Hormonal regulation  
Elements of cardiovascular physiopathology (Chapters VIII and X)
- Pressure overload (Chapter VIII)
- Volume overload (Chapter VIII)
- Breach of contractility (Chapter VIII)
- The vicious circle of heart failure (Chapter X)
- Circulatory insufficiencies (Chapter X)
   - Syncopes
   - Shocks

Biochemistry and normal and pathological human physiology, Respiratory system

The course aims at allowing students to be able to understand human biochemistry and physiology
The different systems will be part of the course:
I. Cardio-vascular system. 
1. Elements of cardio-vascular physiology 2. Cardiac pump 3. Vascular System 4. Cardio-vascular homeostasis : cardiac output and arterial pressure 5. Principles of cardio-vascular physiopathology 6. Arterial hypertension 7. Coronary insufficiency 8. Cardiac failure
II. Respiratory system
1. Introduction to respiratory system 
2. Ventilation
3. Diffusion 
4. Circulation
5. Blood gazes
6. Control of pH
7. Gaz exchanges
8. Respiratory mechanics
9. Control of ventilation
10. Unusual conditions (altitude...). 
 
III. Digestive system 
1. Introduction
2. Regulation processes
3. Energy and metabolism
4. Regulation of intakes
5. Mouth
6. Oesophagus
7. Stomach
8. Hormons of digestive tract
9. Pancreas
10. Intestine absorption 
11. Liver 
12. Colon 
 
IV. Nephro-urinary system 
1. Introduction
2. Glomerular filtration
3. Tubular function
4. Water and ions regulation
5. Kidney pathophysiology 
6. Urinary tract


V. Endocrine system and metabolism
 
The course concerns human biochemistry and physiology, partim endocrine system and metabolism. In particular, it encompasses the following chapters:
1. Introduction
2. Mechanisms of action of hormones
3. The hormones of the energetic metabolism
   Energetic metabolism
   Insulin and diabetes
   Glucagon
   Epinephrine
   Glucocorticoids
   Thyroid hormones
4. Gastro-intestinal hormones
5. Water, electrolytes, and mineral elements
6. Growth
7. Reproduction
8. Cytokines
9. Mediators
 
VI Nervous system
Système sensoriels somatiques : somesthésie, vision, audition, gustation, olfaction
Système moteur somatique : unité motrice, contrôle segmentaire des unités motrices, contrôle supra-segmentaire, apprentissage
Cognition, émotion, comportement
Eveil et conscience
Homéostasie

 

Learning outcomes of the learning unit

Clinical examination - general semiology

Au terme de ces cours, les étudiants pourront conduire une anamnèse et y relever les éléments importants, tenir un dossier et rédiger une observation médicale, réaliser un examen clinique général et mesurer les paramètres vitaux, et identifier les urgences vitales. Ils seront capables d'évaluer la valeur des tests médicaux et de comprendre la signification de la spécificité et de la sensibilité d'un test ainsi que de sa valeur prédictive positive et négative.

Diagnostic measurements - supplementary investigations

At the end of this course, the student will be able to understand the interest of prescribing additional medical imaging or clinical biology examinations and to apply these reasoning to his daily practice.

Special Pharmacology

xxx

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

The objective of the course is to master the principles of biochemistry and physiology of the human endocrine system and of the metabolism of the human organism. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.
More specifically, the learning objectives correspond to the table of contents of the course, described in detail in the "contents of the teaching unit" section.

Biochemistry and normal and pathological human physiology, Digestive system

The objective of the course is to master the principles of biochemistry and physiology of the human systems. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.

Biochemistry and normal and pathological human physiology, Nephro-urinary system

The objective of the course is to master the principles of biochemistry and physiology of the human systems. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.

Biochemistry and normal and pathological human physiology, Cardiovascular system

The objective of the course is to master the principles of biochemistry and physiology of the human cardio-vascular system. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.
More specifically, the learning objectives correspond to the table of contents of the course, described in detail in the "contents of the teaching unit" section.

Biochemistry and normal and pathological human physiology, Respiratory system

The objective of the course is to master the principles of biochemistry and physiology of the human cardio-vascular system. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.

Prerequisite knowledge and skills

Clinical examination - general semiology

Ce cours s'adresse à des étudiants ayant un Bac en soins infirmiers

Diagnostic measurements - supplementary investigations

The basic concepts necessary to understand the course were acquired in nursing training and in the daily practice of nursing.

Special Pharmacology

general pharmacology

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

General Biochemestry; General Physiology

Biochemistry and normal and pathological human physiology, Digestive system

General Biochemestry; General Physiology

Biochemistry and normal and pathological human physiology, Nephro-urinary system

General Biochemestry; General Physiology

Biochemistry and normal and pathological human physiology, Cardiovascular system

General Biochemestry; General Physiology

Biochemistry and normal and pathological human physiology, Respiratory system

General Biochemestry; General Physiology

Planned learning activities and teaching methods

Clinical examination - general semiology

Outre un cours ex cathedra , l'apprentissage se fera au labo de simultation sur des mannequins haute fidélité.

Diagnostic measurements - supplementary investigations

Course ex cathedra.

The acquisition of knowledge is done on the basis of theoretical reminders and specific clinical situations.

Special Pharmacology

xxx

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Lectures with active participation of students. All classes are podcast.

Biochemistry and normal and pathological human physiology, Digestive system

Lectures with active participation of students

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Lectures with active participation of students

Biochemistry and normal and pathological human physiology, Cardiovascular system

Lectures with active participation of students. All classes are podcast.

Biochemistry and normal and pathological human physiology, Respiratory system

Lectures with active participation of students

Mode of delivery (face to face, distance learning, hybrid learning)

Clinical examination - general semiology

Face-to-face course

Diagnostic measurements - supplementary investigations

Face-to-face course

Special Pharmacology

see vade mecum

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Face-to-face delivery

Biochemistry and normal and pathological human physiology, Digestive system

Blended learning


Additional information:

Face-to-face delivery or on-line lessons.

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Blended learning


Additional information:

Face-to-face delivery or on-line lessons

Biochemistry and normal and pathological human physiology, Cardiovascular system

Face-to-face delivery

Biochemistry and normal and pathological human physiology, Respiratory system

Face-to-face delivery or on-line lessons.

Recommended or required readings

Clinical examination - general semiology

Les notes de cours seront disponibles sur my Uliege sous forme de fichiers powerpoint.

Lecture conseillée:

Sémiologie médicale. Baptiste Coustet. Ed Vuibert

Examen clinique éléments de sémiologie médicale. Epstein, Perkin, de Bono, Cookson. De Boeck Université.

Diagnostic measurements - supplementary investigations

The presentations are available on the course's my ulg website.

Special Pharmacology

xxx

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Course syllabus, available on MyULg/eCampus

Biochemistry and normal and pathological human physiology, Digestive system

Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition. D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed<br /><br /> Course syllabus, available on MyULg/eCampus<br /><br /> Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition. D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed<br /><br /> Course syllabus, available on MyULg/eCampus


Many learning objectives can also be reached by referring the following optional textbooks:

Mayo Clinic Medical Neurosciences: Organized by Neurologic Systems and Levels, (6 edn) 2017              Eduardo E. Benarroch, Jeremy K. Cutsforth-Gregory, Kelly D. Flemming. Edition Oxford academic

Neurosciences, 6ème édition, 2019 (traduite en français). D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. Editions de boeck.

 <br /><br /> Course syllabus, available on MyULg/eCampus

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Course syllabus, available on eCampus

Biochemistry and normal and pathological human physiology, Cardiovascular system

Course syllabus, available on MyULg/eCampus

Biochemistry and normal and pathological human physiology, Respiratory system

Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition. D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed

Clinical examination - general semiology

Exam(s) in session

Any session

- In-person

written exam

Diagnostic measurements - supplementary investigations

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire, open-ended questions )

Special Pharmacology

Any session :

- In-person

oral exam

- Remote

oral exam

- If evaluation in "hybrid"

preferred in-person


Additional information:

xxx

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire )


Additional information:

End semester evaluations



The exams are written. They include the following types of questions:

MCQs with certainty coefficients (see note on this subject on the eCampus).


Examinations will take place as on-line (if needed) or presential activities. 

There is no partial exemption for this course, either between the 1st and 2nd session or from one year to the next for the PHARMA, SBIM and DENTIST sections.

However, this rule does not apply to Master of Science in Nursing students. Partial exemptions may be granted.

.    

Biochemistry and normal and pathological human physiology, Digestive system

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire )


Additional information:

End semester evaluations



The exams are written. They include the following types of questions:

MCQs with certainty coefficients (see note on this subject on the eCampus).


Examinations will take place as on-line (if needed) or presential activities. 

There is no partial exemption for this course, either between the 1st and 2nd session or from one year to the next for the PHARMA, SBIM and DENTIST sections.

However, this rule does not apply to Master of Science in Nursing students. Partial exemptions may be granted.

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire )


Additional information:

End semester evaluations



The exams are written. They include the following types of questions:

MCQs with certainty coefficients (see note on this subject on the eCampus).


Examinations will take place as on-line (if needed) or presential activities. 

There is no partial exemption for this course, either between the 1st and 2nd session or from one year to the next for the PHARMA, SBIM and DENTIST sections.

However, this rule does not apply to Master of Science in Nursing students. Partial exemptions may be granted.

Biochemistry and normal and pathological human physiology, Cardiovascular system

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire )


Additional information:

End semester evaluations

Written evaluations will take place in june and in august/september. Evaluations will be organized the same day for all parts of the course Normal and Pathological Human Biochemistry and Physiology (NPHBP). 

For the cardio-vascular module, the exam consists of Multiple Choice Questions (MCQ).

Biochemistry and normal and pathological human physiology, Respiratory system

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire )


Additional information:

End semester evaluations



The exams are written. They include the following types of questions:

MCQs with certainty coefficients (see note on this subject on the eCampus).


Examinations will take place as on-line (if needed) or presential activities. 

There is no partial exemption for this course, either between the 1st and 2nd session or from one year to the next for the PHARMA, SBIM and DENTIST sections.

However, this rule does not apply to Master of Science in Nursing students. Partial exemptions may be granted.

Work placement(s)

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

No training

Biochemistry and normal and pathological human physiology, Nephro-urinary system

No training

Biochemistry and normal and pathological human physiology, Cardiovascular system

No training

Biochemistry and normal and pathological human physiology, Respiratory system

No training

Organisational remarks and main changes to the course

Special Pharmacology

xxx

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

No remark

Biochemistry and normal and pathological human physiology, Nephro-urinary system

No remark

Biochemistry and normal and pathological human physiology, Cardiovascular system

No remark

Biochemistry and normal and pathological human physiology, Respiratory system

No remark

Contacts

Clinical examination - general semiology

b.lambermont@uliege.be

Diagnostic measurements - supplementary investigations

E Brasseur

Edmond.Brasseur@chuliege.be

Special Pharmacology

Teacher :
Vincent Seutin
Laboratoire de Pharmacologie et GIGA Neurosciences, CHU Tour 4 (B36)
Avenue Hippocrate 15, 4000 Liège

Secretary :
Madame N. Lacroix (même adresse), Nastasia.Lacroix@uliege.be   Tél : +32 4 366 25 24

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
 

Biochemistry and normal and pathological human physiology, Digestive system

Prof Didier CATALDO

didier.cataldo@uliege.be

Tel : 04 366 2521 

Mme Jessica THYS (administrative assistent)

Jessica.thys@uliege.be

 

 Pr Philippe Kolh

Philippe.kolh@uliege.be

04/3665196

04/3668445 (secretary)

 

Prof Gaetan GARRAUX

Tél : 04 3665950

ggarraux@uliege.be

Pr Philippe Kolh

Philippe.kolh@uliege.be

04/3665196

04/3668445 (secretary)

 

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Prof Didier CATALDO

didier.cataldo@uliege.be

Tel : 04 366 2521 

Mme Jessica THYS (administrative assistent)

Jessica.thys@uliege.be

 

Biochemistry and normal and pathological human physiology, Cardiovascular system

Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
 

Biochemistry and normal and pathological human physiology, Respiratory system

Prof Didier CATALDO
didier.cataldo@uliege.be
Tel : 04 366 2521 
Mme Jessica THYS (administrative assistent)
Jessica.thys@uliege.be
 
 Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
 
Prof Gaetan GARRAUX
Tél : 04 3665950
ggarraux@uliege.be

Association of one or more MOOCs